References

vavilov

Вавиловский журнал генетики и селекции

Vavilov Journal of Genetics and Breeding

2500-3259

Institute of Cytology and Genetics of Siberian Branch of the RAS

10.18699/VJ17.294

vavilov-1226

Research Article

ФИЛОГЕНЕТИКА

HIGH-THROUGHPUT PHENOTYPING

Поведенческие и нейрональные реакции на кон- и гетероспецифические обонятельные сигналы у двух видов мышей – Mus musculus и Mus spicilegus

Behavioral and neuronal responses of two mouse species, Mus musculus and Mus spicilegus, to con- and heterospecific olfactory signals

Котенкова

Е. В.

Kotenkova

E. V.

Москва.

Moscow.

evkotenkova@yandex.ru

Ромащенко

А. В.

Romashchenko

A. V.

Новосибирск.

Novosibirsk.

Мальцев

А. Н.

Maltsev

A. N.

Москва.

Moscow.

Институт проблем экологии и эволюции им. А.Н. Северцова Российской академии наук.РоссияSevertsov Institute of Ecology and Evolution RAS.Russian Federation

Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук; Институт вычислительных технологий Сибирского отделения Российской академии наук.РоссияInstitute of Cytology and Genetics SB RAS; Institute of Computational Technologies SB RAS.Russian Federation

2017

23122017

217788794

2017

Котенкова Е.В., Ромащенко А.В., Мальцев А.Н.

Kotenkova E.V., Romashchenko A.V., Maltsev A.N.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://vavilov.elpub.ru/jour/article/view/1226

The behavioral and neuronal responses of the males of two closely related species of mice (Mus musculus wagneri, M. spicilegus) to the urine odors of estrus con- and heterospecific females were studied. In two-choice odor tests males significantly longer investigated odor of conspecific females in comparison with heterospecific ones. To investigate neuronal activation in the main and accessory olfactory bulbs (MOB and AOB), one of the methods of functional tomography – manganese-enhanced MRI ( ME-MRI) – was used. There was a significant increase in Mn2+ accumulation in the dorsal section of the posterior part of the MOB in male M. m. wagneri and M. spicilegus exposed to odor of conspecific females compared with the control group males (odor not exposed). There was a local significant increase in manganese accumulation in the dorsal region of the anterior part of the MOB in the case of the exposure of odor of a heterospecific female. The exposure of heptanone-2 to mice resulted not only in an increase in Mn2+ accumulation in certain zones, but also in a significant decrease in the accumulation of Mn2+ in the rest of the olfactory bulbs. A significant increase in the accumulation of MRI contrast in AOB was observed in males only in the case of female urine-conspecific odor exposure. The results support the previously stated assumption of a significant difference in chemical communication systems in two species of mice. A comparison of these results and results obtained previously demonstrated the absence of any differences in behavioral and neuronal responses to con- and heterospecific odors of the house mouse subspecies allopatric (M. m. wagneri) and sympatric (M. m. musculus) to M. spicilegus. This fact does not allow us to assume the effect of the mechanism of “reinforcement” in the process of evolution in the formation of precopulatory reproductive isolation between the sympatric species M. spicilegus and M. musculus.

домовые мышиM. spicilegusM. musculusобонятельные сигналымарганец-усиленная томографиядополнительная обонятельная системаосновная обонятельная система

house miceM. spicilegusM. musculusolfactory signalsmanganese-enhanced tomographyadditional olfactory systemmain olfactory system

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The authors declare that there are no conflicts of interest present.