<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vavilov</journal-id><journal-title-group><journal-title xml:lang="ru">Вавиловский журнал генетики и селекции</journal-title><trans-title-group xml:lang="en"><trans-title>Vavilov Journal of Genetics and Breeding</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2500-3259</issn><publisher><publisher-name>Institute of Cytology and Genetics of Siberian Branch of the RAS</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vavilov-219</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>СТРУКТУРА ГЕНОМА И ХРОМОСОМНЫЙ АНАЛИЗ РАСТЕНИЙ</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бадаева</surname><given-names>Е. Д.</given-names></name></name-alternatives><email xlink:type="simple">katerinabadaeva@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Салина</surname><given-names>Е. А.</given-names></name></name-alternatives><email xlink:type="simple">salina@bionet.nsc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное учреждение науки Институт общей генетики&#13;
им. Н.И. Вавилова РАН, Москва, Россия<country>Россия</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение «Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук», Новосибирск, Россия<country>Россия</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>11</day><month>01</month><year>2015</year></pub-date><volume>17</volume><issue>4/2</issue><fpage>1017</fpage><lpage>1043</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бадаева Е.Д., Салина Е.А., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Бадаева Е.Д., Салина Е.А.</copyright-holder><copyright-holder xml:lang="en">Бадаева Е.Д., Салина Е.А.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vavilov.elpub.ru/jour/article/view/219">https://vavilov.elpub.ru/jour/article/view/219</self-uri><abstract><p>Термин «геном» впервые был введен немецким ботаником Гансом Винклером в 1920 г. для обозначения генетического материала, составляющего гаплоидный набор хромосом у растений. Гаплоидный набор хромосом обозначают как 1n, а диплоидный – 2n. </p><p>Хромосомный анализ растений – это комплекс методов, направленных на выявление особенностей хромосомной организации генома вида, идентификацию его хромосом, анализ их функциональной активности. История хромосомного анализа насчитывает свыше 130 лет и в настоящее время он широко используется в генетических исследованиях растений.</p><p>Митотические хромосомы первым наблюдал В. Флемминг в 1879 г., изучая деление клеток аксолотля. Немного позже (в 1882 г.) Э. Страсбургер обнаружил сходные структуры в клетках растений, а в 1881 г. Э. Бальбиани описал гигантские хромосомы из клеток слюнных желез личинок Chironomus plumosus. В 1883 г. Дж.Л.М. Ван Бенеден показал, что число хромосом в гаметах вдвое меньше, чем в соматических клетках, а Т. Бовери предположил (1890), что редукция числа хромосом происходит во время оогенеза. Однако для обозначения структур, появляющихся в ядре во время деления клетки, эти авторы использовали различные названия («нити», «петли», «сегменты», «элементы» и др.). Термин хромосома(chromo – окрашенное, soma – тело) первым применил немецкий ученый В. Вальдейер (W. Waldeyer) в 1888 г., поскольку описанные структуры интенсивно окрашивались основными красителями.</p></abstract><funding-group xml:lang="ru"><funding-statement>программа ФНИ (проект № VI.53.1.5.), РФФИ, программа РАН «Динамика и сохранение генофондов»</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Сергеева Е.М., Салина Е.А. Мобильные элементы и эволюция генома растений // Вавилов. журн. генет. и селекции. 2011. Т. 15. № 2. С. 585–600.</mixed-citation><mixed-citation xml:lang="en">Сергеева Е.М., Салина Е.А. Мобильные элементы и эволюция генома растений // Вавилов. журн. генет. и селекции. 2011. Т. 15. № 2. С. 585–600.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Badaeva E.D., Dedkova O.S., Gay G. et al. Chromosomal rearrangements in wheat: their types and distribution // Genome. 2007. V. 50. No. 10. P. 907–926.</mixed-citation><mixed-citation xml:lang="en">Badaeva E.D., Dedkova O.S., Gay G. et al. Chromosomal rearrangements in wheat: their types and distribution // Genome. 2007. V. 50. No. 10. P. 907–926.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Bennett M.D. Plant genome values: How much do we know? // Proc. Natl Acad. Sci. USA. 1998. V. 95. No. 5. P. 2011–2016.</mixed-citation><mixed-citation xml:lang="en">Bennett M.D. Plant genome values: How much do we know? // Proc. Natl Acad. Sci. USA. 1998. V. 95. No. 5. P. 2011–2016.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Cabrera A., Martín A. et al. In situ comparative mapping (ISCM) of Glu-1 loci in Triticum and Hordeum // Chrom. Res. 2002. V. 10. No. 1. P. 49–54.</mixed-citation><mixed-citation xml:lang="en">Cabrera A., Martín A. et al. In situ comparative mapping (ISCM) of Glu-1 loci in Triticum and Hordeum // Chrom. Res. 2002. V. 10. No. 1. P. 49–54.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Chen R., Song W., Li X., An Z. Chromosome G-banding in plants by inducing with trypsin and urea[ast] // Cell Res. 1994. V. 4. No. 1. P. 79–87.</mixed-citation><mixed-citation xml:lang="en">Chen R., Song W., Li X., An Z. Chromosome G-banding in plants by inducing with trypsin and urea[ast] // Cell Res. 1994. V. 4. No. 1. P. 79–87.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Choulet F., Wicker T., Rustenholz C. et al. Megabase level sequencing reveals contrasted organization and evolution patterns of the wheat gene and transposable element spaces // Plant Cell. 2010. V. 22. No. 6. P. 1686–1701.</mixed-citation><mixed-citation xml:lang="en">Choulet F., Wicker T., Rustenholz C. et al. Megabase level sequencing reveals contrasted organization and evolution patterns of the wheat gene and transposable element spaces // Plant Cell. 2010. V. 22. No. 6. P. 1686–1701.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">de Jong J.H., Fransz P., Zabel P. High resolution FISH in plants – techniques and applications // Trends Plant Sci. 1999. V. 4. No. 7. P. 258–263.</mixed-citation><mixed-citation xml:lang="en">de Jong J.H., Fransz P., Zabel P. High resolution FISH in plants – techniques and applications // Trends Plant Sci. 1999. V. 4. No. 7. P. 258–263.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Doležel J., Šimková H., Kubaláková M. Chromosome genomics in the Triticeae // Genetics and Genomics of the Triticeae / Eds G.J. Muehlbauer, C. Feuillet. N.Y., Springer, 2009. 7. Part 2 (Tools, Resources and Approaches). P. 285–316.</mixed-citation><mixed-citation xml:lang="en">Doležel J., Šimková H., Kubaláková M. Chromosome genomics in the Triticeae // Genetics and Genomics of the Triticeae / Eds G.J. Muehlbauer, C. Feuillet. N.Y., Springer, 2009. 7. Part 2 (Tools, Resources and Approaches). P. 285–316.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Endo T.R., Gill B.S. The deletion stocks of common wheat // J. Hered. 1996. V. 87. No. 4. P. 295–307.</mixed-citation><mixed-citation xml:lang="en">Endo T.R., Gill B.S. The deletion stocks of common wheat // J. Hered. 1996. V. 87. No. 4. P. 295–307.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Fukui K.N., Suzuki G., Lagudah E.S. et al. Physical arrangement of retrotransposon-related repeats in centromeric regions of wheat // Plant Cell Physiol. 2001. V. 42. No. 2. P. 189–196.</mixed-citation><mixed-citation xml:lang="en">Fukui K.N., Suzuki G., Lagudah E.S. et al. Physical arrangement of retrotransposon-related repeats in centromeric regions of wheat // Plant Cell Physiol. 2001. V. 42. No. 2. P. 189–196.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Fukui K., Minezawa M., Kamisugi Y. et al. Microdissection of plant chromosomes by argon-ion laser beam // Theor. Appl. Genet. 1992. V. 84. No. 7. P. 787–791.</mixed-citation><mixed-citation xml:lang="en">Fukui K., Minezawa M., Kamisugi Y. et al. Microdissection of plant chromosomes by argon-ion laser beam // Theor. Appl. Genet. 1992. V. 84. No. 7. P. 787–791.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Gale M.D., Devos K.M. Comparative genetics in the grasses // Proc. Natl Acad. Sci. USA. 1998. V. 95. No. 5. P. 1971–1974.</mixed-citation><mixed-citation xml:lang="en">Gale M.D., Devos K.M. Comparative genetics in the grasses // Proc. Natl Acad. Sci. USA. 1998. V. 95. No. 5. P. 1971–1974.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Gill B.S., Friebe B., Endo T.R. Standard karyotype and nomenclature system for description of chromosome bands and structural aberrations in wheat (Triticum aestivum) // Genome. 1991. V. 34. No. 5. P. 830–839.</mixed-citation><mixed-citation xml:lang="en">Gill B.S., Friebe B., Endo T.R. Standard karyotype and nomenclature system for description of chromosome bands and structural aberrations in wheat (Triticum aestivum) // Genome. 1991. V. 34. No. 5. P. 830–839.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Hřibová E., Doleželová M., Town C.D. Isolation and characterization of the highly repeated fraction of the banana genome // Cytogenet. Genome Res. 2007. V. 119. No. 3/4. P. 268–274.</mixed-citation><mixed-citation xml:lang="en">Hřibová E., Doleželová M., Town C.D. Isolation and characterization of the highly repeated fraction of the banana genome // Cytogenet. Genome Res. 2007. V. 119. No. 3/4. P. 268–274.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Jones J.D.G., Flavell R.B. The mapping of highly-repeated DNA families and their relationship to C-bands in chromosomes of Secale cereale // Chromosoma. 1982. V. 86. No. 5. P. 595–612.</mixed-citation><mixed-citation xml:lang="en">Jones J.D.G., Flavell R.B. The mapping of highly-repeated DNA families and their relationship to C-bands in chromosomes of Secale cereale // Chromosoma. 1982. V. 86. No. 5. P. 595–612.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Jung C., Claussen U., Horstemke B. et al. A DNA library from an individual Beta patellaris chromosome conferring nematode resistance obtained by microdissection of meiotic metaphase chromosomes // Plant Mol. Biol. 1992. V. 20. No. 3. P. 503–511.</mixed-citation><mixed-citation xml:lang="en">Jung C., Claussen U., Horstemke B. et al. A DNA library from an individual Beta patellaris chromosome conferring nematode resistance obtained by microdissection of meiotic metaphase chromosomes // Plant Mol. Biol. 1992. V. 20. No. 3. P. 503–511.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kakeda K., Yamagata H. Immunological analysis of chromosome replication in barley, rye, and durum wheat by using an anti-BrdU antibody // Hereditas. 1992. V. 116. P. 67–70. Kato A. High-density fl uorescence in situ hybridization signal detection on barley (Hordeum vulgare L.) chromosomes with improved probe screening and reprobing procedures // Genome. 2011. V. 54. No. 2. P. 151–159.</mixed-citation><mixed-citation xml:lang="en">Kakeda K., Yamagata H. Immunological analysis of chromosome replication in barley, rye, and durum wheat by using an anti-BrdU antibody // Hereditas. 1992. V. 116. P. 67–70. Kato A. High-density fl uorescence in situ hybridization signal detection on barley (Hordeum vulgare L.) chromosomes with improved probe screening and reprobing procedures // Genome. 2011. V. 54. No. 2. P. 151–159.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Lysak M.A., Pecinka A., Schubert I. Recent progress in chromosome painting of Arabidopsis and related species // Chrom. Res. 2003. V. 11. No. 3. P. 195–204.</mixed-citation><mixed-citation xml:lang="en">Lysak M.A., Pecinka A., Schubert I. Recent progress in chromosome painting of Arabidopsis and related species // Chrom. Res. 2003. V. 11. No. 3. P. 195–204.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Meyers L.A., Levin D.A. On the abundance of polyploids in fl owering plants // Evolution. 2006. V. 60. No. 6. P. 1198–1206.</mixed-citation><mixed-citation xml:lang="en">Meyers L.A., Levin D.A. On the abundance of polyploids in fl owering plants // Evolution. 2006. V. 60. No. 6. P. 1198–1206.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Moore G. Cereal chromosome structure, evolution, and pairing // Annu. Rev. Plant Physiol. Plant Mol. Biol. 2000. V. 51. No. 1. P. 195–222.</mixed-citation><mixed-citation xml:lang="en">Moore G. Cereal chromosome structure, evolution, and pairing // Annu. Rev. Plant Physiol. Plant Mol. Biol. 2000. V. 51. No. 1. P. 195–222.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Pardue M.L., Gall J.G. Chromosomal localization of mouse satellite DNA // Science. 1970. V. 168. No. 3937. P. 1356–1358.</mixed-citation><mixed-citation xml:lang="en">Pardue M.L., Gall J.G. Chromosomal localization of mouse satellite DNA // Science. 1970. V. 168. No. 3937. P. 1356–1358.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Ren Y., Zhang Z., Liu J. et al. An integrated genetic and cytogenetic map of the cucumber genome // PLoS ONE. 2009. V. 4. No. 6. e5795.</mixed-citation><mixed-citation xml:lang="en">Ren Y., Zhang Z., Liu J. et al. An integrated genetic and cytogenetic map of the cucumber genome // PLoS ONE. 2009. V. 4. No. 6. e5795.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Salina E.A. Tandem repeats in evolution of polyploid wheat and Aegilops section Sitopsis // Israel J. Plant Sci. 2007. V. 55. No. 3/4. P. 231–240.</mixed-citation><mixed-citation xml:lang="en">Salina E.A. Tandem repeats in evolution of polyploid wheat and Aegilops section Sitopsis // Israel J. Plant Sci. 2007. V. 55. No. 3/4. P. 231–240.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Sandhu D., Gill K.S. Gene-containing regions of wheat and the other grass genomes // Plant Physiol. 2002. V. 128. No. 3. P. 803–811.</mixed-citation><mixed-citation xml:lang="en">Sandhu D., Gill K.S. Gene-containing regions of wheat and the other grass genomes // Plant Physiol. 2002. V. 128. No. 3. P. 803–811.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Santos J.L., Lacadena J.R., Cermeño M.C., Orellana J. Nucleolar organiser activity in wheat-barley chromosome addition lines // Heredity. 1984. V. 52. No. 3. P. 425–429.</mixed-citation><mixed-citation xml:lang="en">Santos J.L., Lacadena J.R., Cermeño M.C., Orellana J. Nucleolar organiser activity in wheat-barley chromosome addition lines // Heredity. 1984. V. 52. No. 3. P. 425–429.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Schmidt T., Heslop-Harrison J.S. Genomes, genes and junk: the large-scale organization of plant chromosomes // Trends Plant Sci. 1998. V. 3. No. 5. P. 195–199.</mixed-citation><mixed-citation xml:lang="en">Schmidt T., Heslop-Harrison J.S. Genomes, genes and junk: the large-scale organization of plant chromosomes // Trends Plant Sci. 1998. V. 3. No. 5. P. 195–199.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Tek A., Jiang J. The centromere regions of potato chromosomes contain megabasе-sized tandem arrays of telomere-similar sequence // Chromosoma. 2004. V. 113. No. 2. P. 77–83.</mixed-citation><mixed-citation xml:lang="en">Tek A., Jiang J. The centromere regions of potato chromosomes contain megabasе-sized tandem arrays of telomere-similar sequence // Chromosoma. 2004. V. 113. No. 2. P. 77–83.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Vosa C.G. Heterochromatin recognition with fl uorochromes // Chromosoma. 1970. V. 30. No. 3. P. 366–372.</mixed-citation><mixed-citation xml:lang="en">Vosa C.G. Heterochromatin recognition with fl uorochromes // Chromosoma. 1970. V. 30. No. 3. P. 366–372.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Vrana J., Kubalakova M., Simkova H. et al. Flow sorting of mitotic chromosomes in common wheat (Triticum aestivum L.) // Genetics. 2000. V. 156. No. 4. P. 2033–2041.</mixed-citation><mixed-citation xml:lang="en">Vrana J., Kubalakova M., Simkova H. et al. Flow sorting of mitotic chromosomes in common wheat (Triticum aestivum L.) // Genetics. 2000. V. 156. No. 4. P. 2033–2041.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Weiss H., Scherthan H. Aloe spp. – plants with vertebrate-like telomeric sequences // Chromosome Res. 2002. V. 10. No. 2. P. 155–164.</mixed-citation><mixed-citation xml:lang="en">Weiss H., Scherthan H. Aloe spp. – plants with vertebrate-like telomeric sequences // Chromosome Res. 2002. V. 10. No. 2. P. 155–164.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">ДОПОЛНИТЕЛЬНАЯ ЛИТЕРАТУРА</mixed-citation><mixed-citation xml:lang="en">ДОПОЛНИТЕЛЬНАЯ ЛИТЕРАТУРА</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Инге-Вечтомов С.Г. Генетика с основами селекции. Н-Л.: Издательство, 2010.</mixed-citation><mixed-citation xml:lang="en">Инге-Вечтомов С.Г. Генетика с основами селекции. Н-Л.: Издательство, 2010.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Картель Н.А., Макеева Е.Н., Мезенко А.М. Генетика: энциклопедический словарь. Минск: Тэхналогiя, 1999.</mixed-citation><mixed-citation xml:lang="en">Картель Н.А., Макеева Е.Н., Мезенко А.М. Генетика: энциклопедический словарь. Минск: Тэхналогiя, 1999.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Льюин Б. Гены. Изд-во «Мир», 1987.</mixed-citation><mixed-citation xml:lang="en">Льюин Б. Гены. Изд-во «Мир», 1987.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Appels R., Morris R., Gill B.S., May C. Chromosome Biology. Boston а.о.: Kluwer Acad. Publ., 1998. P. 256–265.</mixed-citation><mixed-citation xml:lang="en">Appels R., Morris R., Gill B.S., May C. Chromosome Biology. Boston а.о.: Kluwer Acad. Publ., 1998. P. 256–265.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
