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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vavilov</journal-id><journal-title-group><journal-title xml:lang="ru">Вавиловский журнал генетики и селекции</journal-title><trans-title-group xml:lang="en"><trans-title>Vavilov Journal of Genetics and Breeding</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2500-3259</issn><publisher><publisher-name>Institute of Cytology and Genetics of Siberian Branch of the RAS</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vavilov-338</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>HIGH-PERFORMANCE SIMULATIONS OF POPULATION-GENETIC PROCESSES IN BACTERIAL COMMUNITIES USING THE HAPLOID EVOLUTIONARY CONSTRUCTOR SOFTWARE</article-title><trans-title-group xml:lang="en"><trans-title>HIGH-PERFORMANCE SIMULATIONS OF POPULATION-GENETIC PROCESSES IN BACTERIAL COMMUNITIES USING THE HAPLOID EVOLUTIONARY CONSTRUCTOR SOFTWARE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Mustafin</surname><given-names>Z. S.</given-names></name><name name-style="western" xml:lang="en"><surname>Mustafin</surname><given-names>Z. S.</given-names></name></name-alternatives><email xlink:type="simple">lashin@bionet.nsc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Matushkin</surname><given-names>Yu. G.</given-names></name><name name-style="western" xml:lang="en"><surname>Matushkin</surname><given-names>Yu. G.</given-names></name></name-alternatives><email xlink:type="simple">lashin@bionet.nsc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Lashin</surname><given-names>S. A.</given-names></name><name name-style="western" xml:lang="en"><surname>Lashin</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">lashin@bionet.nsc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">The Federal research center Institute of cytology and genetics the Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia<country>Россия</country></aff><aff xml:lang="en">Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia&#13;
Novosibirsk National Research State University, Novosibirsk, Russia<country>Россия</country></aff><aff xml:lang="en">Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia&#13;
Novosibirsk National Research State University, Novosibirsk, Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>22</day><month>01</month><year>2015</year></pub-date><volume>18</volume><issue>4/2</issue><fpage>1039</fpage><lpage>1045</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Mustafin Z.S., Matushkin Y.G., Lashin S.A., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Mustafin Z.S., Matushkin Y.G., Lashin S.A.</copyright-holder><copyright-holder xml:lang="en">Mustafin Z.S., Matushkin Y.G., Lashin S.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vavilov.elpub.ru/jour/article/view/338">https://vavilov.elpub.ru/jour/article/view/338</self-uri><abstract><p>Three high-performance versions of the Haploid Evolutionary Constructor program are presented (<ext-link xlink:href="http://evol-constructor.bionet.nsc.ru" ext-link-type="uri">http://evol-constructor.bionet.nsc.ru</ext-link>). The software was designed for simulating the functioning and evolution of microbial communities. These high-performance versions are to be run on systems with shared and distributed memory, using CPU and/or GPU. Almost linear acceleration has been achieved on clusters and multi-core CPU. On GPU systems, the simulation time was reduced to several minutes (dozens of hours on CPU).</p></abstract><trans-abstract xml:lang="en"><p>Three high-performance versions of the Haploid Evolutionary Constructor program are presented (<ext-link xlink:href="http://evol-constructor.bionet.nsc.ru" ext-link-type="uri">http://evol-constructor.bionet.nsc.ru</ext-link>). The software was designed for simulating the functioning and evolution of microbial communities. These high-performance versions are to be run on systems with shared and distributed memory, using CPU and/or GPU. Almost linear acceleration has been achieved on clusters and multi-core CPU. On GPU systems, the simulation time was reduced to several minutes (dozens of hours on CPU).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Microbial community</kwd><kwd>parallelization</kwd><kwd>simulation</kwd><kwd>evolution</kwd><kwd>optimization</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Microbial community</kwd><kwd>parallelization</kwd><kwd>simulation</kwd><kwd>evolution</kwd><kwd>optimization</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>grants: RFBR 12-07-00671-а, project VI.61.1.2, interdisciplinary SB RAS project 47</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ashlock D., McEachern A. A simulation of bacterial communities // IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB). IEEE. 2011. P. 1–8.</mixed-citation><mixed-citation xml:lang="en">Ashlock D., McEachern A. 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