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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vavilov</journal-id><journal-title-group><journal-title xml:lang="ru">Вавиловский журнал генетики и селекции</journal-title><trans-title-group xml:lang="en"><trans-title>Vavilov Journal of Genetics and Breeding</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2500-3259</issn><publisher><publisher-name>Institute of Cytology and Genetics of Siberian Branch of the RAS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18699/VJ16.139</article-id><article-id custom-type="elpub" pub-id-type="custom">vavilov-803</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГЕНЕТИКА И СЕЛЕКЦИЯ РАСТЕНИЙ НА ИММУНИТЕТ, КАЧЕСТВО, ПРОДУКТИВНОСТЬ И СТРЕССОУСТОЙЧИВОСТЬ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANIMAL GENETICS AND BREEDING</subject></subj-group></article-categories><title-group><article-title>Генетические маркеры в мясном овцеводстве</article-title><trans-title-group xml:lang="en"><trans-title>Genetic markers in sheep meat breeding</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дейкин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Deykin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва, Россия</p></bio><bio xml:lang="en"><p>Moscow, Russia</p></bio><email xlink:type="simple">deikin@igb.ac.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селионова</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Selionova</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ставрополь, Россия</p></bio><bio xml:lang="en"><p>Stavropol, Russia</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Криворучко</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivoruchko</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ставрополь, Россия</p></bio><bio xml:lang="en"><p>Stavropol, Russia</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коваленко</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovalenko</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ставрополь, Россия</p></bio><bio xml:lang="en"><p>Stavropol, Russia</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трухачев</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Truhachev</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ставрополь, Россия</p></bio><bio xml:lang="en"><p>Stavropol, Russia</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное учреждение науки Институт биологии гена Российской академии наук<country>Россия</country></aff><aff xml:lang="en">IInstitute of Gene Biology, Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Федеральное государственное бюджетное научное учреждение «Всероссийский научно-исследовательский институт овцеводства и козоводства»<country>Россия</country></aff><aff xml:lang="en">All-Russian Scientific Research Institute of Sheep and Goat Breeding<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования «Ставропольский государственный аграрный университет»<country>Россия</country></aff><aff xml:lang="en">Stavropol State Agrarian University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>29</day><month>12</month><year>2016</year></pub-date><volume>20</volume><issue>5</issue><fpage>576</fpage><lpage>583</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дейкин А.В., Селионова М.И., Криворучко А.Ю., Коваленко Д.В., Трухачев В.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Дейкин А.В., Селионова М.И., Криворучко А.Ю., Коваленко Д.В., Трухачев В.И.</copyright-holder><copyright-holder xml:lang="en">Deykin A.V., Selionova M.I., Krivoruchko A.Y., Kovalenko D.V., Truhachev V.I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vavilov.elpub.ru/jour/article/view/803">https://vavilov.elpub.ru/jour/article/view/803</self-uri><abstract><p>Мясное животноводство, в том числе овцеводство, – важнейшая отрасль сельского хозяйства. Повышение производительности и улучшение качества мяса рассматриваются сегодня как приоритеты развития отрасли. В последнее время значительные результаты в мясном овцеводстве получены благодаря использованию достижений генетики. В селекционных программах обычно отбирали производителей на основании качества потомства, родственников или предков. В то же время применение молекулярно- генетической технологии может вывести такие работы на новый методический уровень. На сегодняшний день все еще нерешенной остается проблема установления достоверной связи между признаками продуктивности и генетическими маркерами, поскольку в отличие, например, от моногенных заболеваний, признаки продуктивности обладают комплексным характером и их проявление зависит от баланса между различными физиологическими функциями, нарушение в котором, даже при кажущейся положительной роли превалирующего элемента, может привести к снижению продуктивности в целом. Селекция на основе генетических маркеров продуктивности направлена на работу с животными с высоким генетическим потенциалом по приросту живой массы и качеству мяса. В обзоре описаны перспективные гены – потенциальные маркеры продуктивности в мясном овцеводстве. Подробно рассмотрено использование гена гормона роста, каллипигии, кальпаина и кальпастатина в качестве перспективных генетических маркеров для селекции овец. Вместе с тем необходимо констатировать, что, несмотря на многочисленные сообщения о потенциальных генетических маркерах продуктивности, заметного влияния на повышение экономических показателей в овцеводстве молекулярно- генетические методы пока не оказали.</p></abstract><trans-abstract xml:lang="en"><p>Cattle breeding, including sheep farming, is an important sector of agriculture. Increasing productivity and improving meat quality are considered today as the priorities in the industry. Significant advances have been achieved in sheep breeding through the use of genetics. The commonplace of all selection programs is using manufacturers selected on the basis of the quality of the offspring, relatives or ancestors. At the same time, using the achievements of molecular genetics can lead breeding to a new methodological level. The problem of finding reliable communication between productivity features and genetic markers has not yet been solved, because productivity is a set of features (unlike, for example, monogenic diseases) and its expression depends on the balance between various physiological functions. By contrast, imbalance may cause reduced productivity as a whole even if there is a positive role of prevailing element. Selection on the basis of genetic markers of productivity aims to work with animals with high genetic potential for weight gain and meat quality. This review considers promising genes – potential markers of productivity in sheep farming, such as growth hormone gene, callipyge, calpain and calpastatin, which have promise as genetic markers for sheep selection. However, it should be stated that in spite of numerous reports about potential genetic markers of productivity there is still no data about the influence of molecular genetic methods on improving the economic performance of sheep selection.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>генетические маркеры продуктивности</kwd><kwd>гормон роста</kwd><kwd>каллипигия</kwd><kwd>кальпаин</kwd><kwd>кальпастатин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>genetic markers of productivity</kwd><kwd>growth hormone</kwd><kwd>callipyge phenotype</kwd><kwd>calpain</kwd><kwd>calpastatin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Anthony R.V., Liang R., Kayl E.P., Pratt S.L. The growth hormone/prolactin gene family in ruminant placentae. J. Reprod. Fertil. Suppl. 1995;49:83-95.</mixed-citation><mixed-citation xml:lang="en">Anthony R.V., Liang R., Kayl E.P., Pratt S.L. 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