Breeding and selection of mini-pigs in the ICG SB RAS

The article considers methods used for breeding and selection of mini-pigs in the ICG, SB RAS, the theoretical justifcation of these methods and the purposes for which they are used. We showed the genealogical structure of the herd and the contribution of inbreeding to the genetic similarity of modern representatives of genealogical lines and families with the founders of the breeding group. We characterized the phenotypic diversity of the ICG mini-pigs in colours, weight categories, types of growth and features of constitution. We listed measures supporting genetic diversity in the herd of the ICG mini-pigs. We explained the possibility of using similarity indices calculated by using portions of the ancestors’ blood (genome) for the selection of parental pairs and the evaluation of genetic consolidation of the herd. We showed that the average index of similarity between males and females, calculated by using portions of the ancestors’ blood, in the ICG minipigs is close to the limit value. It turned out that effective evaluation of the genetic potential of mini-pigs in growth rate and fnal size of individuals is only possible under the condition of a rich and full feeding of young animals. The time scale of estimation of growth of live weight of the ICG mini-pigs for three weight categories allocated in the selection group is presented. The types of growth and development of mini-pigs observed in the ICG breeding group and the type inherent to individuals in the small weight category are considered. We justifed the minimum live weight of a newborn piglet in the herd of the ICG mini-pigs. Values of optimal multiple pregnancy for the three categories of ICG mini-pig sows were calculated.

1. Bekenev V.A. Technology of Pig Keeping and Breeding. St. Petersburg: Lan Publ., 2012. (in Russian)

2. Zhivotovskiy L.A. Populational Biometry. Moscow: Nauka Publ., 1991. (in Russian)

3. Instruction for Appraisal of Pigs. Main Department of Animal Husbandry and the State Inspectorate for Breeding. Moscow: Kolos Publ., 1976. (in Russian)

4. Iohanson I., Rendel J., Gravert O. Genetics and Breeding of Farm Animals. Moscow: Kolos Publ., 1970. (in Russian)

5. Kabanov V.D. Increasing Pig Productivity. Moscow: Kolos Publ., 1983. (in Russian)

6. Kudryavtsev P.N. Breeding Business in Pig Husbandry. Moscow: OGIZ; Selkhozgiz, 1948. (in Russian)

7. Kuleshov P.N. The Theoretical Work on Herdbook Breeding. Moscow: OGIZ; Selkhozgiz, 1947. (in Russian)

8. Nikitin S.V., Knyazev S.P. Selection and Adaptation in Domestic Pig Populations. Saarbrucken. Lambert Academy Publ., 2015. (in Russian)

9. Nikitin S.V., Knyazev S.P., Shatokhin K.S., Goncharenko G.M., Zaporozhets V.I., Ermolayev V.I. Juvenile coat colours in mini-pigs at ICG. Vavilovskii Zhurnal Genetiki i Selektsii = Vavilov Journal of Genetics and Breeding. 2017;21(6):638-645. DOI 10.18699/VJ17.280. (in Russian)

10. Nikitin S.V., Shatokhin K.S., Knyazev S.P., Goncharenko G.M., Zaporozhets V.I., Ermolayev V.I. Polymorphic loci of coat color in mini-pigs. Vavilovskii Zhurnal Genetiki i Selektsii = Vavilov Journal of Genetics and Breeding. 2016;20(5):584-595. DOI 10.18699/VJ16.180 (in Russian)

11. Petukhov V.L., Tikhonov V.N., Zheltikov A.I., Korotkevich O.S., Kamaldinov E.V., Fridcher A.A. The Gene and Phene Pools of the Siberian Northern Breed and the Siberian Black-and-White Breed Group of Pigs. Novosibirsk: NSAU Publ., 2010. (in Russian)

12. Pond W.G., Houpt K.A. The Biology of the Pig. Cornell University Press, Ithaca, New York, 1983. (Russ. ed.: Pond U.Dj., Khoupt K.A. The Biology of the Pig. Moscow: Kolos Publ., 1983.)

13. Stankova N.V., Savina M.A., Kapanadze G.D. The formation of new lines of Svetlogorsk minipigs. Biomeditsina = Biomedicine. 2017;3:95-101. (in Russian)

14. Striovski E. MiniPigs (Pet pigs). Maintenance and Care. Moscow: Aquarium-Print Publ., 2008. (in Russian)

15. Tikhonov V.N. Laboratory Minipigs. Genetics and Biomedical Use. Novosibirsk: SB RAS Publ., 2010. (in Russian)

16. Shatokhin K.S., Deeva V.S., Goncharenko G.M., Grishina N.B., Goryacheva T.S., Akulich E.G., Kononenko E.V., Yermolayev V.I., Nikitin S.V. Genetic features of minipigs from the Institute of Cytology and Genetics, Novosibirsk. Vestnik NGAU = Bulletin of the Novosibirsk State Agrarian University. 2014a;30(1):75-81. (in Russian)

17. Shatokhin K.S., Zaporozhets V.I., Goncharenko G.M., Nikitin S.V. Characterization of minipigs with regard to their exterior and behavioral traits. Sibirskiy Vestnik Selskohozyaistvennoy Nauki = Siberian Herald of Agricultural Science. 2013;4:31-36. (in Russian)

18. Shatokhin K.S., Knyazev S.P., Goncharenko G.M., Nikitin S.V. The effect of allele introduction on the status of the allele pool of blood group system loci in the population of minipigs in the Institute of Cytology and Genetics, Novosibirsk. Vestnik NGAU = Bulletin of the Novosibirsk State Agrarian University. 2014b;33(4):119-124. (in Russian)

19. Shatokhin K.S., Knyazev S.P., Ermolaev V.I., Goncharenko G.M., Deeva V.S., Zaporozhets V.I., Orlova K.S., Nikitin S.V. Biodiversity of ICG minipigs as laboratory bioresources. Vestnik NGAU = Bulletin of the Novosibirsk State Agrarian University. 2016; 41(4):67-74. (in Russian)

20. Andersson L., Plastow G. Molecular genetics of coat colour variation. In: Rothschild M.F., Ruvinsky A. (Eds.). The Genetics of the Pig. 2nd еd. CAB International, 2011;38-50.

21. Bollen P.J.A., Madsen L.W., Meyer O., Ritskes-Hoitinga J. Growth differences of male and female Göttingen minipigs during ad libitum feeding: a pilot study. Lab. Anim. 2005;39(1):80-93.

22. Fontanezi L., Russo V. Molecular genetics of coat colour in pigs. Acta Argiculturae Slovenica, Ljubljana. 2013;4:15-20.

23. Nikitin S.V., Knyazev S.P., Shatokhin K.S. Miniature pigs of ICG as a model object for morphogenetic research. Russ. J. Genet.: Appl. Res. 2014;4(6):511-522.

24. Nikitin S.V., Lobkov Yu.I. A lethal allele of gene Spotted (grey spots) in pigs. Russ. J. Genet. 1996;32(8):973-977.

25. Rozkot M., Václavková Е., Bělková J. Minipigs as laboratory animals – review. Res. Pig Breeding. 2015;9(2):10-14.

26. Simianer H., Köhn F. Genetic management of the Göttingen Minipig population. J. Pharmacol. Toxicol. Methods. 2010;62:221-226.

27. Stricker-Krongrad А., Shoemake C.R., Pereira M.E., Gad S.C., Brocksmith D., Bouchard G.F. Miniature swine breeds in toxicology and drug safety assessments: what to expect during clinical and pathology evaluations. Toxicol. Pathol. 2016;44(3):421-427.