МАТЕМАТИЧЕСКОЕ МОДЕЛИРОВАНИЕ СИНТЕЗА БИОЭТАНОЛА И МОЛОЧНОЙ КИСЛОТЫ ТЕРМОФИЛЬНЫМИ БАКТЕРИЯМИ РОДА Geobacillus

В работе представлена разработанная и адаптированная к имеющимся экспериментальным данным математическая модель биосинтеза биоэтанола и молочной кислоты в клетках Geobacillus sрp. Показано, что математическая модель позволяет осуществлять in silico планирование экспериментов с бактерией Geobacillus sрp. методами молекулярно-генетической инженерии, предсказывать динамику изменения концентрации синтезируемых биоэтанола и молочной кислоты в зависимости от молекулярно-генетических манипуляций с активностью ферментов метаболической системы.

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