ФИЗИОЛОГИЧЕСКАЯ ГЕНЕТИКА
Аннотация
Генетика и физиология, какова взаимосвязь двух предметов, двух наук? Возможно, генетик скажет, что генетика предваряет физиологию, ибо гены детерминируют все физиологические системы. Но ведь и геном формируется в процессе отбора фенотипов, а фенотип – это физиология, но… физиология детерминирована генами. Похоже на сказку «про белого бычка». Однако кольцо разомкнется, если принять во внимание, что отнюдь не все в физиологии предопределено генами и что не только генетическая изменчивость является предметом наследования; что существует эпигенетическая изменчивость, связанная с физиологическими процессами, и что имеется множество других «что», о чем ниже.
Об авторе
А. Л. МаркельРоссия
Список литературы
1. Иванов В.И. Феногенетика // Большая Советская Энциклопедия / Ред. А.М. Прохоров. М.: Сов. Энциклопедия, 1977. Т. 27. 624 с.
2. Лобашев М.Е. Сигнальная наследственность. Исследования по генетике / Ред. М.Е. Лобашев. Л., 1961.
3. Abel E. Paternal contribution to fetal alcohol syndrome // Addict. Biol. 2004. V. 9. 127–133 discussion 135–136.
4. Abel E.L., Bilitzke P. Paternal alcohol exposure: paradoxical effect in mice and rats // Psychopharmacology (Berl). 1990. V. 100. P. 159–164.
5. Abel E.L., Moore C., Waselewsky D. et al. Effects of cocaine hydrochloride on reproductive function and sexual behavior of male rats and on the behavior of their offspring // J. Androl. 1989. V. 10. P. 17–27.
6. Abel E.L., Tan S.E. Effects of paternal alcohol consumption on pregnancy outcome in rats // Neurotoxicol. Teratol. 1988. V. 10. P. 187–192.
7. Anderson L.M., Riffl e L., Wilson R. et al. Preconceptional fasting of fathers alters serum glucose in offspring of mice // Nutrition. 2006. V. 22. P. 327–331.
8. Andersson M., Simmons L.W. Sexual selection and mate choice // Trends Ecol. Evol. 2006. V. 21. P. 296–302.
9. Badyaev A.V., Uller T. Parental effects in ecology and evolution: mechanisms, processes and implications // Philos. Trans R. Soc. B. 2009. V. 364. P. 1169–1177.
10. Bagot R.C., Meaney M.J. Epigenetics and the biological basis of gene × environment interactions // J. Am. Acad. Child. Adolesc. Psychiatry. 2010. V. 49. P. 752–771.
11. Balter M. Are humans still evolving? // Science. 2005. V. 309. P. 234–237.
12. Bonner J.T. The Evolution of Culture in Animals. Princeton: Princeton Univ. Press, 1980.
13. Burger J., Kirchner M., Bramanti B. et al. Absence of the lactase persistence-associated allele in early Neolithic Europeans // Proc. Natl Acad. Sci. USA. 2007. V. 104. P. 3736–3741.
14. Champagne F.A. Epigenetic mechanisms and the transgenerational effects of maternal care // Front. Neuroendocrinol. 2008. V. 29. P. 386–397.
15. Crews D. Epigenetics, brain, behavior and the environment // Hormones. 2010. V. 9. P. 41–50.
16. Curley J.P., Mashoodh R., Champagne F.A. Epigenetics and the origins of paternal effects // Horm Behav. 2011. V. 59. P. 305–314.
17. Cubas P., Vincent C., Coen E. An epigenetic mutation responsible for natural variation in fl oral symmetry // Nature. 1999. V. 401. P. 157–161.
18. Curley J.P., Champagne F.A., Bateson P., Keverne E.B. Transgenerational effects of impaired maternal care on behaviour of offspring and grandoffspring // Anim. Behav. 2008. V. 75. P. 1551–1561.
19. Curley J.P., Davidson S., Bateson P., Champagne F.A. Social enrichment during postnatal development induces transgenerational effects on emotional and reproductive behaviour in mice // Front. Behav. Neurosci. 2009. V. 3. P. 1–14.
20. Danchin É., Charmantier A., Champagne F.A. et al. Beyond DNA: integrating inclusive inheritance into an extended theory of evolution // Nature Rev. Genet. 2011. V. 12. P. 475–486.
21. Danchin É., Wagner R.H. Inclusive heritability: combining genetic and nongenetic information to study animal culture // Oikos. 2010. V. 119. P. 210–218.
22. Dawkins R. The Extended Phenotype. Oxford: Oxford Univ. Press, 1982. 307 p.
23. Dolinoy D.C., Weidman J.R., Waterland R.A., Jirtle R.L. Maternal genistein alters coat color and protects avy mouse offspring from obesity by modifying the fetal epigenome // Envir. Health Perspect. 2006. V. 14. No. 4. P. 567–572.
24. Falconer D.S. Introduction to Quantitative Genetics. N.Y.: Longman, 1981.
25. Gasparini J., McCoy K.D., Haussy C. et al. Induced maternal response to the Lyme disease spirochaete Borrelia burgdorferi senus lato in a colonial seabird, the kittiwake, Rissa tridactyla // Proc. R. Soc. Lond. B. 2001. V. 268. P. 647–650.
26. Gasparini J., McCoy K., Staszewski V. et al. Dynamics of anti-Borrelia antibodies in Black-legged Kittiwakes (Rissa tridactyla) chicks suggest a maternal educational effect // Can. J. Zool. 2006. V. 84. P. 623–627.
27. Golding J. Sex-specifi c, male-line transgenerational responses in humans // Eur. J. Hum. Genet. 2006. V. 14. P. 159–166.
28. Griffith S.C., Owens I.P.F., Burke T. Environmental determination of a sexually selected trait // Nature. 1999. V. 400. P. 358–360.
29. Guglielmino C.R., Viganotti C., Hewlett B., Cavalli-Sforza L.L. Cultural variation in Africa: Role of mechanisms of transmission and adaptation // Proc. Natl Acad. Sci. USA. 1995. V. 92. P. 7585–7589.
30. Hager R., Cheverud J.M., Wolf J.B. Maternal effects as the cause of parent-of-origin effects that mimic genomic imprinting // Genetics. 2008. V. 178. P. 1755–1762.
31. Jablonka E., Szathmáry E. The evolution of information storage and heredity // Trends Ecol. Evol. 1995. V. 10. P. 206–211.
32. Jaenisch R. Celebrating 10 years of hESC lines: an interview with Rudolf Jaenisch // Stem Cells. 2008. V. 26. No. 12. P. 3005–3007.
33. Jones C.G., Lawton J.H., Shachak M. Positive and negative effects of organisms as physical ecosystem engineers // Ecology. 1997. V. 78. P. 1946–1957.
34. Kaati G., Bygren L.O., Edvinsson S. Cardiovascular and diabetes mortality determined by nutrition during parents’ and grandparents’ slow growth period // Eur. J. Hum. Genet. 2002. V. 10. P. 682–688.
35. Kaati G., Bygren L.O., Pembrey M., Sjostrom M. Transgenerational response to nutrition, early life circumstances and longevity // Eur. J. Hum. Genet. 2007. V. 15. P. 784–790.
36. Kendrick K.M., Hinton M.R., Atkins K. et al. Mothers determine sexual preferences // Nature. 1998. V. 395. P. 229–230.
37. Kruuk L.E.B., Hadfi eld J.D. How to separate genetic and environmental causes of similarity between relatives // J. Evol. Biol. 2007. V. 20. P. 1890–1903.
38. Kruuk L.E.B. Estimating genetic parameters in natural populations using the ‘animal model’ // Phil. Trans. R. Soc. Lond. B. 2004. V. 359. P. 873–890.
39. Kylafi s G., Loreau M. Ecological and evolutionary consequences of niche construction for its agent // Ecol. Lett. 2008. V. 11. P. 1072–1081.
40. Lederberg J. The meaning of epigenetics // The Scientist. 2001. V. 15. No. 18. P. 6.
41. Lehmann L. The adaptive dynamics of niche constructing traits in spatially subdivided populations: evolving posthumous extended phenotypes // Evolution. 2008. V. 62. P. 549–566.
42. Lewontin R.C. The triple helix: gene, organism and environment. Cambridge: Harvard Univ. Press, 2000.
43. Lumey L.H. Decreased birthweights in infants after maternal in utero exposure to the Dutch famine of 1944–1945 // Paediatr. Perinat. Epidemiol. 1992. V. 6. Issue 2. P. 240–253.
44. Maternal Effects in Mammals / Eds D. Maestripieri, J.M. Mateo. Chicago (IL): Univ. of Chicago Press, 2009.
45. Marshall D.J., Uller T. When is a maternal effect adaptive? // Oikos. 2007. V. 116. P. 1957–1963.
46. Mazer S.J., Gorchov D.L. Parental effects on progeny phenotype in plants: distinguishing genetic and environmental causes // Evolution. 1996. V. 50. P. 44–53.
47. McClintock B. Mutable loci in maize // Carnegie Institution of Washington Yearbook. 1951. V. 50. P. 174–181.
48. McGlothlin J.W., Brodie E.D. How to measure indirect genetic effects: the congruence of trait-based and variance-partitioning approaches // Evolution. 2009. V. 63. P. 1785–1795.
49. McGlothlin J.W., Moore A.J., Wolf J.B., Brodie E.D. Interacting phenotypes and the evolutionary process. III. Social selection // Evolution. 2010. V. 64. P. 2558–2574.
50. McGowan P.O., Sasaki A., D’Alessio A.C. et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse // Nat. Neurosci. 2009. V. 12. P. 342–348.
51. McGraw-Hill. Phenogenetics // McGraw-Hill dictionary of scientifi c and technical terms / Ed. S.P. Parker. McGraw-Hill, 2003. 2380 p.
52. Meaney M.J., Szyf M. Maternal care as a model for experiencedependent chromatin plasticity? // Trends Neurosci. 2005. V. 28. P. 456–463.
53. Mesoudi A. Cultural evolution: how Darwinian theory can explain human culture and synthesize the social sciences. Chicago: Univ. of Chicago Press, 2011.
54. Mesoudi A., Whiten A., Laland K.N. Is human cultural evolution Darwinian? Evidence reviewed from the perspective of The Origin of Species // Evolution. 2004. V. 58. P. 1–11.
55. Mesoudi A., Whiten A., Laland K.N. Towards a unifi ed science of cultural evolution // Behav. Brain Sci. 2006. V. 29. P. 329–383.
56. Mill J., Tang T., Kaminsky Z. et al. Epigenomic profiling reveals DNA-methylation changes associated with major psychosis // Am. J. Hum. Genet. 2008. V. 82. P. 696–711.
57. Morgan T.H. The Scientifi c Basis of Evolution. London: Faber and Faber, 1932.
58. Mousseau T.A., Fox C.W. The adaptive signifi cance of maternal effects // Trends Ecol. Evol. 1998. V. 13. P. 403–407.
59. Odling-Smee F.J. Niche-constructing phenotypes // The role of behavior in evolution / Ed. H.C. Plotkin. Cambridge: MIT Press, 1988. P. 73–132.
60. Odling-Smee F.J. Niche inheritance: a possible basis for classifying multiple inheritance systems in evolution // Biol. Theory. 2007. V. 2. P. 276–289.
61. Odling-Smee J., Laland K.N. Ecological inheritance and cultural inheritance: what are they and how do they differ? // Biol. Theory. 2011. V. 6. P. 220–230.
62. Odling-Smee F.J. Niche construction, genetic evolution and cultural change // Behav. Processes. 1996. V. 35. P. 195–205.
63. Odling-Smee F.J., Laland K.N., Feldman M.W. Niche Construction. The Neglected Process in Evolution. Monographs in Population Biology 37. Princeton: Princeton Univ. Press, 2003. 472 p.
64. Ondarza R.N. La epigenética, la otra cara de la genética // Mensaje Bioquímico. 2012. V. 36. P. 200–211.
65. Pembrey M.E., Bygren L.O., Kaati G. et al. Sex-specific, male-line transgenerational responses in humans // Eur. J. Hum. Genet. 2006. V. 14. P. 159–166.
66. Plomin R., DeFries J.C., McGuffi n P., Craig I.W. Behavioral genetics in the postgenomic era // Amer. Psychological Association. 2002.
67. Qvarnstrom A., Price T.D. Maternal effects, paternal effects and sexual selection // Trends Ecol. Evol. 2001. V. 16. P. 95–100.
68. Richerson P., Boyd R. Not by genes alone: how culture transformed human evolution. Chicago: Univ. Chicago Press, 2005.
69. Rossiter M.C. Incidence and consequences of inherited environmental effects // Ann. Rev. Ecol. Syst. 1996. V. 27. P. 451–476.
70. Silver M., Di Paolo E. Spatial effects favour the evolution of niche construction // Theor. Popul. Biol. 2006. V. 20. P. 387–400.
71. Waddington C.H. Genetic assimilation of an acquired character // Evolution. 1953. V. 7. No. 2. P. 118–126.
72. Waddington C.H. Organisers and Genes. Cambridge: Cambridge Univ. Press. UK, 1940, 1947.
73. Wang E.T., Kodama G., Baldi P., Moyzis R.K. Global landscape of recent inferred Darwinian selection for Homo sapiens // Proc. Natl Acad. Sci. USA. 2006. V. 103. P. 135–140.
74. Waterland R.A., Jirtle R.L. Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases // Nutrition. 2004. V. 20. P. 63–68.
75. Weiss K.M. The phenogenetic logic of life // Nature Rev. Genetics. 2005. V. 6. P. 35–46.
76. Wilson A.J., Coltman D.W., Pemberton J.M. et al. Maternal genetic effects set the potential for evolution in a freeliving vertebrate population // J. Evol. Biol. 2005. V. 18. P. 405–414.
77. Wilson A.J., Gelin U., Perron M.-C., Réale D. Indirect genetic effects and the evolution of aggression in a vertebrate system // Proc. R. Soc. B. 2009. V. 276. P. 533–541.
78. Wolf J.B., Wade M.J. What are maternal effects (and what are they not)? // Philos. Trans. R. Soc. B. 2009. V. 364. P. 1107–1115.
79. Wolf J.B., Brodie E.D., Cheverud J.M. et al. Evolutionary consequences of indirect genetic effects // Trends Ecol. Evol. 1998. V. 13. P. 64–69.