ПРОМОТОРЫ ГЕНОВ РАСТЕНИЙ, УЧАСТВУЮЩИХ В ЗАЩИТЕ ОТ ПАТОГЕНОВ

Генные сети, контролирующие устойчивость растений к различным фитопатогенам, весьма сложны, в них могут принимать участие сотни генов. Инфекция вызывает существенные изменения на молекулярно-генетическом, биохимическом, физиологическом и морфологическом уровнях как локально, в месте инвазии, так и системно. Реконструкция генных сетей, отвечающих за защиту растений от патогенных бактерий, грибов и вирусов, необходима для выявления задействованных молекулярных механизмов, а также для разработки новых способов повышения устойчивости хозяйственно ценных растений. Транскрипционная активность генов, участвующих в защите от фитопатогенов, обычно возрастает в ответ на инфекцию, поэтому характеристика их промоторов является важным источником информации для выявления транскрипционных факторов, контролирующих их работу, и для поиска новых генов, участвующих в ответе на инфекцию. Данные о промоторах необходимы для создания устойчивых к фитопатогенам растений методами генной инженерии. В статье представлены данные о промоторах патоген-чувствительных генов с экспериментально проверенным паттерном экспрессии, аннотированных в базе TGP (TransGene Promoters). База TGP может быть использована в качестве источника информации для интерпретации транскриптомных данных и при планировании генно-инженерных экспериментов, направленных на повышение устойчивости растений к патогенам различного происхождения.

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