ПРОМОТОРЫ ГЕНОВ РАСТЕНИЙ, УЧАСТВУЮЩИХ В ЗАЩИТЕ ОТ ПАТОГЕНОВ

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Аннотация

Генные сети, контролирующие устойчивость растений к различным фитопатогенам, весьма сложны, в них могут принимать участие сотни генов. Инфекция вызывает существенные изменения на молекулярно-генетическом, биохимическом, физиологическом и морфологическом уровнях как локально, в месте инвазии, так и системно. Реконструкция генных сетей, отвечающих за защиту растений от патогенных бактерий, грибов и вирусов, необходима для выявления задействованных молекулярных механизмов, а также для разработки новых способов повышения устойчивости хозяйственно ценных растений. Транскрипционная активность генов, участвующих в защите от фитопатогенов, обычно возрастает в ответ на инфекцию, поэтому характеристика их промоторов является важным источником информации для выявления транскрипционных факторов, контролирующих их работу, и для поиска новых генов, участвующих в ответе на инфекцию. Данные о промоторах необходимы для создания устойчивых к фитопатогенам растений методами генной инженерии. В статье представлены данные о промоторах патоген-чувствительных генов с экспериментально проверенным паттерном экспрессии, аннотированных в базе TGP (TransGene Promoters). База TGP может быть использована в качестве источника информации для интерпретации транскриптомных данных и при планировании генно-инженерных экспериментов, направленных на повышение устойчивости растений к патогенам различного происхождения.


Об авторах

О. Г. Смирнова
Федеральное государственное бюджетное учреждение науки Институт цитологии и генетики Сибирского отделения РАН, Новосибирск, Россия Федеральное государственное автономное образовательное учреждение высшего образования Новосибирский национальный исследовательский государственный университет, Новосибирск, Россия
Россия


А. В. Кочетов
Федеральное государственное бюджетное учреждение науки Институт цитологии и генетики Сибирского отделения РАН, Новосибирск, Россия Федеральное государственное автономное образовательное учреждение высшего образования Новосибирский национальный исследовательский государственный университет, Новосибирск, Россия
Россия


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