Preview

Vavilov Journal of Genetics and Breeding

Advanced search

NUCLEOSOME ORGANIZATION IN PLANT DNA SATELLITES

Abstract

Satellite DNA, consisting of tandem repeats, forms heterochromatic regions packed into nucleosomes. Sequence and conformational DNA features responsible for the high efficiency of this package have been sought with a Fourier transform. The curvature profiles in tandem repeats differ significantly from a random model. As many as 50 % of the monomers have a periodicity of DNA bends in the vicinity of 170 bp, fitting the wrapping length of a single nucleosome within two highest-order harmonics in the DNA curvature profile. The nucleosome positioning scheme in subtelomeric satellites in plants differs from that in centromeric satellites.

About the Authors

V. N. Babenko
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
Russian Federation


K. O. Kutashev
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
Russian Federation


V. F. Matvienko
Novosibirsk State University, Novosibirsk, Russia
Russian Federation


References

1. Deal R.B., Henikoff J.G. Henikoff S. Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones // Science. 2010. V. 328. P. 1161–1164.

2. Cohanim A.B., Haran T.E. The coexistence of the nucleosome positioning code with the genetic code on eukaryotic genomes // Nucl. Acids Res. 2009. V. 37. Nо 19. P. 6466–6476.

3. Feller W. An Introduction to Probability Theory and its Applications. V. 2. N.Y.: Wiley, 1971.

4. Gupta S., Dennis J., Thurman R.E. et al. Predicting human nucleosome occupancy from primary sequence // PLoS Comput. Biol. 2008. I4:eI000134.

5. Kaplan N., Moore I.K., Fondufe-Mittendorf Y. et al. The DNA-Encoded nucleosome organization of an eukaryotic genome // Nature. 2009. V. 458. P. 362–366.

6. Kaplan N., Moore I., Fondufe-Mittendorf Y. et al. Nucleosome sequence preferences infl uence in vivo nucleosome organization // Nat. Struct. Mol. Biol. 2010. V. 17. Nо 8. P. 918–920.

7. Karlin S., Altschul S.F. Methods for assessing the statistical signifi cance of molecular sequence features by using general scoring schemes // Proc. Natl Acad. Sci. USA. 1990. V. 87. Nо 6. P. 2264–2268.

8. Kiyama R., Trifonov E.N. What positions nucleosomes? – A model // FEBS Lett. 2002. V. 523. Nо 1/3. P. 7–11.

9. Locke G., Tolkunov D., Moqtaderi Z. et al. High-throughput sequencing reveals a simple model of nucleosome energetic // Proc. Natl Acad. Sci. USA. 2010. V. 107. Nо 49. P. 20998–21003.

10. Macas J., Meszaros T., Nouzova M. PlantSat: a specialized database for plant satellite repeats // Bioinformatics. 2002. V. 18. P. 28–35.

11. Ringrose L. How do RNA sequence, DNA sequence, and chromatin properties regulate splicing? // F1000 Biol. Rep. 2010. 2. Р. 74.

12. Segal E., Widom J. What controls nucleosome positions? // Trends Genet. 2009. V. 25. P. 335–343.

13. Schones D.E., Cui K., Cuddapah S. et al. Dynamic regulation of nucleosome positioning in the human genome // Cell. 2008. V. 132. Nо 5. P. 887–898.

14. Spies N., Nielsen C.B., Padgett R.A., Burge C.B. Biased chromatin signatures around polyadenylation sites and exons // Mol. Cell. 2009. V. 36. Nо 2. P. 245–254.

15. Sussman J.L., Trifonov E.N. Possibility of nonkinked packing of DNA in chromatin // Proc. Natl Acad. Sci. USA. 1978. V. 75. Nо 1. P. 103–107.

16. Tanaka Y., Nakai K. An assessment of prediction algorithms for nucleosome positioning // Genome Inform. 2009. V. 23. Nо 1. P. 169–178.

17. Trifonov E.N. Sequence-dependent deformational anisotropy of chromatin DNA // Nucl. Acids Res. 1980. V. 8. Nо 17. P. 165–171.

18. Trifonov E.N. Cracking the chromatin code: Precise rule of nucleosome positioning // Phys. Life Rev. 2011. V. 8. Nо 1. P. 39–50.

19. Valouev A., Ichikawa J., Tonthat T. et al. A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning // Genome Res. 2008. V. 18. Nо 7. P. 1051–1063.

20. Valouev A., Johnson S.M., Boyd S.D. et al. Determinants of nucleosome organization in primary human cells // Nature. 2011. V. 474. Nо 7352. P. 516–522.

21. Xi L., Fondufe-Mittendor Y., Xia L. et al. Predicting nucleosome positioning using a duration Hidden Markov Model // BMC Bioinformatics. 2010. doi:10.1186/1471-2105-11-346.


Review

Views: 585


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2500-3259 (Online)