DETECTION SYSTEM OF A NEW-GENERATION BIOANALYTICAL DEVICE
Abstract
We designed and manufactured a system for detection of antibodies/antigenes in biological fluids. This system records the kinetics of free immunodiffusion of fluorescent nanocomplexes inside the channels of a microfluid module of a new-generation bioanalytical device. The system consists of four parallel excitation channels, a system for fluorescence detection, and an image-processing program. Antibody/antigen concentrations below 0,1 μg/ml can be detected in biological fluids.
About the Authors
E. V. Sysoev
Technological Design Institute of Scientifi c Instrument Engineering SB RAS, Novosibirsk, Russia
Russian Federation
Russian Federation
A. K. Potashnikov
Technological Design Institute of Scientifi c Instrument Engineering SB RAS, Novosibirsk, Russia
Russian Federation
Russian Federation
Y. V. Obidin
Technological Design Institute of Scientifi c Instrument Engineering SB RAS, Novosibirsk, Russia
Russian Federation
Russian Federation
T. N. Goryachkovskaya
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
Russian Federation
Russian Federation
V. S. Bazin
Technological Design Institute of Scientifi c Instrument Engineering SB RAS, Novosibirsk, Russia
Russian Federation
Russian Federation
V. M. Popik
Budker Institute of Nuclear Physics SB RAS, Novosibirsk, Russia
Russian Federation
Russian Federation
S. E. Peltek
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
Russian Federation
Russian Federation
N. A. Kolchanov
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
Novosibirsk National Research State University, Novosibirsk, Russia
National Research Centre «Kurchatov Institute», Moscow, Russia
Russian Federation
Russian Federation
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